Institut Curie / Cnrs Umr 3347/ Inserm U1021 Normal and Pathological Signaling : from the Embryo to the Innovative Therapy of Cancers
نویسنده
چکیده
Melanoma is a very aggressive tumor originating from neural-crest derived melanocytes. The transformation of normal melanocytes into melanoma cells is a multistep process. It is crucial to elucidate the molecular and cellular mechanisms of melanocyte development (specially the molecular network that controls the induction of neural crest) and transformation, to improve the prevention, early diagnosis, prognosis and therapy.
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تاریخ انتشار 2011